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Key Documents

90240

Sigma-Aldrich

Glyceryl triacetate

≥99.0% (GC)

Synonyme(s) :

1,2,3-Triacetoxypropane, 1,2,3-Triacetylglycerol, Glycerol triacetate, Triacetin

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About This Item

Formule linéaire :
(CH3COOCH2)2CHOCOCH3
Numéro CAS:
Poids moléculaire :
218.20
Numéro Beilstein :
1792353
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352211
ID de substance PubChem :
Nomenclature NACRES :
NA.25

Niveau de qualité

Pureté

≥99.0% (GC)

Forme

liquid

Indice de réfraction

n20/D 1.431

Point d'ébullition

258-260 °C (lit.)

Densité

1.158 g/mL at 20 °C

Type de lipide

saturated FAs

Chaîne SMILES 

CC(=O)OCC(COC(C)=O)OC(C)=O

InChI

1S/C9H14O6/c1-6(10)13-4-9(15-8(3)12)5-14-7(2)11/h9H,4-5H2,1-3H3

Clé InChI

URAYPUMNDPQOKB-UHFFFAOYSA-N

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Application


  • Epigenetic priming targets tumor heterogeneity to shift transcriptomic phenotype of pancreatic ductal adenocarcinoma towards a Vitamin D susceptible state.: This groundbreaking study utilizes glyceryl triacetate as part of an epigenetic priming strategy to sensitize pancreatic ductal adenocarcinoma to Vitamin D, marking a significant advancement in cancer treatment modalities (He et al., 2024).

  • Glyceryl triacetate promotes blood-brain barrier recovery after ischemic stroke through lipogenesis-mediated IL-33 in mice.: Research demonstrates glyceryl triacetate′s effectiveness in enhancing blood-brain barrier repair post-ischemic stroke via lipogenesis pathways, offering insights into novel stroke recovery treatments (Wei et al., 2023).

  • Development of A Nanostructured Lipid Carrier-Based Drug Delivery Strategy for Apigenin: Experimental Design Based on CCD-RSM and Evaluation against NSCLC In Vitro.: This study details the formulation of a nanostructured lipid carrier incorporating glyceryl triacetate, optimized for delivering apigenin to combat non-small cell lung cancer, emphasizing the potential of glyceryl triacetate in targeted therapy applications (Wang et al., 2023).

  • Are New Phthalate Ester Substitutes Safer than Traditional DBP and DiBP Comparative Endocrine-Disrupting Analyses on Zebrafish Using In Vivo, Transcriptome, and In Silico Approaches.: Investigating glyceryl triacetate as a safer alternative to traditional phthalate esters, this study explores its lower endocrine-disrupting effects, contributing to safer industrial and pharmaceutical applications (Tan et al., 2023).

  • Glyceryl triacetate feeding in mice increases plasma acetate levels but has no anticonvulsant effects in acute electrical seizure models.: This research evaluates the biochemical impact of glyceryl triacetate on plasma acetate levels, providing valuable data on its metabolic effects despite a lack of anticonvulsant properties in specific seizure models (Xu et al., 2022).


Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

298.4 °F - closed cup

Point d'éclair (°C)

148 °C - closed cup

Équipement de protection individuelle

Eyeshields, Gloves


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