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Merck
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Key Documents

04-039

Sigma-Aldrich

Anti-20S proteasome subunit α2 Antibody, clone MCP21

clone MCP21, Upstate®, from mouse

Synonyme(s) :

HC3, proteasome subunit alpha type 2

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.28

Source biologique

mouse

Niveau de qualité

100

Forme d'anticorps

ascites fluid

Type de produit anticorps

primary antibodies

Clone

MCP21, monoclonal

Espèces réactives

human, rabbit, bovine

Fabricant/nom de marque

Upstate®

Technique(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotype

IgG1

Numéro d'accès NCBI

NM_002787.3

Numéro d'accès UniProt

P25787

Conditions d'expédition

dry ice

Informations sur le gène

bovine ... Psma2(539141)
human ... PSMA2(5683)
rabbit ... Psma2(100355295)

Spécificité

Recognizes proteasome subunit alpha type 2.

Immunogène

Human placenta derived proteasomes

Application

Anti-20S proteasome subunit α2 Antibody, clone MCP21 detects level of 20S proteasome subunit α2 & has been published & validated for use in IP, WB, IH.
Research Category
Protein Trafficking
Research Sub Category
Ubiquitin & Ubiquitin Metabolism

Description de la cible

26 kDa

Forme physique

100 µL concentration of 1mg/mL purified ascites in PBS containing 0.01M sodium azide. Dilute to working strength with phosphate buffered saline pH 7.2-7.4.
Ascites
Format: Purified

Stockage et stabilité

Stable for 1 year at -20°C from date of shipment for up to 12 months.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Tomasz Klaus et al.
Scientific reports, 6, 30938-30938 (2016-08-04)
Mouse immunoglobulins M (IgMs) that recognize human blood group antigens induce haemagglutination and are used worldwide for diagnostic blood typing. Contrary to the current belief that IgGs are too small to simultaneously bind antigens on two different erythrocytes, we obtained
G Zhong et al.
The Journal of experimental medicine, 191(9), 1525-1534 (2000-05-03)
We have previously shown that the obligate intracellular pathogen chlamydia can suppress interferon (IFN)-gamma-inducible major histocompatibility complex (MHC) class II expression in infected cells by degrading upstream stimulation factor (USF)-1. We now report that chlamydia can also inhibit both constitutive
Impact of ageing on proteasome structure and function in human lymphocytes
Carrard, Geraldine, et al
The International Journal of Biochemistry & Cell Biology, 35, 728-739 (2003)
K B Hendil et al.
The Biochemical journal, 305 ( Pt 1), 245-252 (1995-01-01)
The proteasome or multicatalytic endopeptidase from eukaryotic cells consists of at least 14 subunits that fall into two families, alpha and beta. Subunit-specific monoclonal antibodies against ten different subunits of human proteasomes have been produced, together with an antibody that
Tomasz Klaus et al.
Frontiers in immunology, 9, 1096-1096 (2018-06-08)
Mouse IgG3 is highly protective against several life-threatening bacteria. This isotype is the only one among mouse IgGs that forms non-covalent oligomers, has increased functional affinity to polyvalent antigens, and efficiently agglutinates erythrocytes. IgG3 also triggers the complement cascade. The

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