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03-0146-00

Millipore

SMC® Amyloid Beta 42 High Sensitivity Kit

1 kit sufficient for 96 wells, input: serum, plasma, cerebrospinal fluid (CSF)

Synonyme(s) :

Abeta 1-42 immunoassay kit, Abeta 42 Single Molecule Counting Kit, Abeta 42 immunoassay kit, Abeta 42 ultra-sensitive Immunoassay

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About This Item

Code UNSPSC :
12161503
Nomenclature NACRES :
NA.84

Niveau de qualité

200

Utilisation

 kit sufficient for 96 wells

Espèces réactives

human, rat, mouse

Fabricant/nom de marque

SMC®

assay range

sensitivity: 0.98 pg/mL
(lower limit of quantification)
inter-assay cv: <20%
intra-assay cv: <15%
standard curve range: 0.24-250 pg/mL

Technique(s)

ELISA: suitable
single molecule counting: suitable

Entrée

serum
plasma
cerebrospinal fluid (CSF)

Compatibilité

for use with SMCxPRO® and Erenna<TMSYMBOL></TMSYMBOL> (validated)

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Description générale

The SMC® Amyloid β1-42 High Sensitivity Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format.

Assay protocols are similar to existing sandwich ELISA methods with two key differences:
1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification.
2)The Erenna and SMCxPRO® immunoassay systems detect analytes using Single Molecule Counting (SMC®) technology.

Spécificité

The capture antibody recognizes the C-terminal end of Amyloid beta 1-42, conferring specificity for Aβ42. No significant cross-reactivity to Aβ38 and Aβ40 was observed.

Informations légales

SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictogrammes

Skull and crossbonesHealth hazard
GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B - STOT RE 2 Inhalation

Organes cibles

Respiratory Tract

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

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Chia-Liang Tsai et al.
Journal of clinical medicine, 8(10) (2019-10-09)
Nondemented people with a family history of Alzheimer's disease (ADFH) and the ApoE-4 allele have been demonstrated to show a trend for a higher probability of cognitive decline and aberrant levels of cognitive-related biomarkers. However, the potential interactive effects on

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