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841118P

Avanti

Egg Trans PE

L-α-phosphatidylethanolamine, transphosphatidylated (Egg, Chicken), powder

Synonyme(s) :

L-a-Phosphatidylethanolamine Transphosphatidylated (prepared from Egg PC)

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About This Item

Numéro CAS:
383907-63-9
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

powder

Conditionnement

pkg of 1 × 25 mg (841118P-25mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand 841118P

Type de lipide

phosphoglycerides

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O

Catégories apparentées

Description générale

Phosphatidylethanolamine (PE) is a phospholipid found in all living organisms. The phosphatidylethanolamine (PE) headgroup is a zwitterion, with a negatively charged phosphate group and positively charged free amine group. The egg yolk contains high levels of unsaturated PE which accounts to 83.10%.

Application

Egg Trans PE is suitable for use:
  • in the preparation of zwitterionic liposome for binding assay
  • as a component in optimized theranostic nanoemulsion (NE) formulations
  • in the preparation of large unilamellar vesicles (LUVs) for detecting the leakage of intraliposomal carboxyfluorescein caused by anthraquinones

Actions biochimiques/physiologiques

Phosphatidylethanolamine (PE) along with other phospholipids forms the backbone of biological membranes. PE is known to regulate autophagy. The autophagic membranes possesses PE with high degree of unsaturation. Egg yolk PE has high radical scavenging activity owing to antioxidant potential.

Conditionnement

5 mL Clear Glass Sealed Ampule (841118P-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids

Certificats d'analyse (COA)

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The
The Membranes of Cells, 22(3) (2016)
Membrane permeabilization by trypanosome lytic factor, a cytolytic human high density lipoprotein
Harrington JM, et al.
Journal of biological and chemical chronicles, 284(20), 13505-13512 (2009)
In Vitro and In Vivo evaluation of a novel folate-targeted theranostic nanoemulsion of docetaxel for imaging and improved anticancer activity against ovarian cancers
Patel NR, et al.
Cancer Biochemistry Biophysics, 19(7), 554-564 (2018)
Niravkumar R Patel et al.
Cancer biology & therapy, 19(7), 554-564 (2018-05-09)
Ovarian cancer ranks fifth in cancer related deaths for women in USA. The high mortality rate associated with ovarian cancer is due to diagnosis at later stages of disease and the high recurrence rate of 60-80%. Recurrent ovarian cancers are
Mark L Bannister et al.
Circulation research, 116(8), 1324-1335 (2015-02-05)
Flecainide, a class 1c antiarrhythmic, has emerged as an effective therapy in preventing arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia (CPVT) refractory to β-adrenergic receptor blockade. It has been proposed that the clinical efficacy of flecainide in CPVT is
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