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840514P

Avanti

16:0-18:1 Phosphatidylethanol

Avanti Research™ - A Croda Brand 840514P, powder

Synonyme(s) :

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol (sodium salt)

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About This Item

Formule empirique (notation de Hill):
C39H74NaO8P
Numéro CAS:
322647-55-2
Poids moléculaire :
724.96
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

powder

Conditionnement

pkg of 2 × 100 mg (840514P-200mg)
pkg of 1 × 25 mg (840514P-25mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand 840514P

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

[H][C@@](COP([O-])(OCC)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

Catégories apparentées

Description générale

Phosphatidylethanol (PEth) is a phospholipid, that is generated in the presence of ethanol in cell membranes. PEths like PEth 16:0/18:1, PEth 18:1/18:1, and PEth 16:0/16:0 possesses a common phosphoethanol head. Two fatty acid chains of variable length and degree of saturation are bound to this head group.
Phosphatidylethanol (PEth) represents a group of glycerophospholipid homologues generated by substitution of ethanol for the lipid headgroup by the phospholipase D enzyme. Since the formation of PEth is specifically dependent on ethanol, the diagnostic specificity of PEth as an alcohol biomarker is theoretically 100%.

Application

16:0-18:1 Phosphatidylethanol may be used in surface planar bilayers (SPBs) formation.

Actions biochimiques/physiologiques

Phosphatidylethanols (PEths) serves as crucial biomarkers of alcohol consumption.

Conditionnement

5 mL Clear Glass Sealed Ampule (840514P-200mg)
5 mL Clear Glass Sealed Ampule (840514P-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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18:1 Phosphatidylmethanol 1,2-dioleoyl-sn-glycero-3-phosphomethanol (sodium salt), powder

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840420P

18:1 Phosphatidylmethanol

Surface planar bilayers of phospholipids used in protein membrane reconstitution: an atomic force microscopy study
Domenech O, et al.
Colloids and Surfaces. B, Biointerfaces, 47(1), 102-106 (2006)
Alexandra Schröck et al.
Bioanalysis, 6(17), 2285-2294 (2014-11-11)
For early diagnosis and therapy of alcohol-related disorders, alcohol biomarkers are highly valuable. Concerning specificity, indirect markers can be influenced by nonethanol-related factors, whereas direct markers are only formed after ethanol consumption. Sensitivity of the direct markers depends on cut-offs
David Wensbo Posaric et al.
Analytical and bioanalytical chemistry, 406(19), 4735-4744 (2014-05-29)
Various phosphatidylethanol (PEth) derivatives, the corresponding reversed positional isomers (RPI-PEths), lyso-PEth-16:0, and penta-deuterium-labeled PEth analogs (d5-PEths), were synthesized by enzyme-independent synthetic routes. A general solvent system consisting of a mixture of acetone-d6 and methanol-d4 (97:3; v/v) was found to provide
The detection of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol and ethyl glucuronide in human umbilical cord
Jones J, et al.
American Journal of Analytical Chemistry, 3(12), 800-800 (2012)
Anders Isaksson et al.
Drug testing and analysis, 3(4), 195-200 (2011-03-26)
Phosphatidylethanol (PEth) represents a group of glycerophospholipid homologues where ethanol by phospholipase D has been bound at the position that normally contains an amino-alcohol. Since the formation of PEth is specifically dependent on ethanol, the diagnostic specificity of PEth as
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