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Merck
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Key Documents

921971

Sigma-Aldrich

Droplet generator chip - Multi channel design

Fluidic 912, COC

Synonyme(s) :

Microfluidic chip

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About This Item

Code UNSPSC :
42142600
Nomenclature NACRES :
NA.23

Description

Microfludic chip x1

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Application

Microfluidic generation of droplets can produce highly monodispersed droplets with high frequency (up to hundreds of kHz). Interest in droplet-based microfluidic systems has grown substantially, because microfluidics offers the ability to handle very small volumes (μl to fl) of fluids, provides better mixing, encapsulation, sorting, and sensing. Microfluidics can be used for high throughput experimentation. Microfluidic-based droplets have many diverse applications such as particle synthesis and chemical analysis. Highly controlled droplet production also makes single cell analysis, or drug testing possible.

Droplet generator chip - Multi channel design, Fluidic 912, COC is made of (Cyclic olefin copolymer). It provides eight identical droplet generator units with a nozzle size of 80 μm on one chip. The continuous phase is introduced through one Mini Luer inlet, which separates into two channels. Operation of one unit of Fluidic 912 therefore requires a microfluidic pump with the ability to control two individual flows, one for the continuous and one for the disperse phase.

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Recent advances of controlled drug delivery using microfluidic platforms
Li X, et al.
Advanced Drug Delivery Reviews, 128 , 3-28 (2018)
Microfluidic-assisted fabrication of carriers for controlled drug delivery.
Santos H A, et al.
Lab on a chip, 17, 1856-1883 (2017)
Dongfei Liu et al.
Lab on a chip, 17(11), 1856-1883 (2017-05-10)
The microfluidic technique has brought unique opportunities toward the full control over the production processes for drug delivery carriers, owing to the miniaturisation of the fluidic environment. In comparison to the conventional batch methods, the microfluidic setup provides a range
Sharma T Sanjay et al.
Advanced drug delivery reviews, 128, 3-28 (2017-09-19)
Conventional systematically-administered drugs distribute evenly throughout the body, get degraded and excreted rapidly while crossing many biological barriers, leaving minimum amounts of the drugs at pathological sites. Controlled drug delivery aims to deliver drugs to the target sites at desired

Articles

Microfluidics for Nanoencapsulation of Nucleic Acids

Microfluidic assembly improves polyamine nanoencapsulation of nucleic acids, overcoming challenges like polydispersity and poor reproducibility.

Microfluidics for Nanoencapsulation of Nucleic Acids

Microfluidic assembly improves polyamine nanoencapsulation of nucleic acids, overcoming challenges like polydispersity and poor reproducibility.

Microfluidics for Nanoencapsulation of Nucleic Acids

Microfluidic assembly improves polyamine nanoencapsulation of nucleic acids, overcoming challenges like polydispersity and poor reproducibility.

Microfluidics for Nanoencapsulation of Nucleic Acids

Microfluidic assembly improves polyamine nanoencapsulation of nucleic acids, overcoming challenges like polydispersity and poor reproducibility.

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