Accéder au contenu
Merck
Toutes les photos(2)

Key Documents

View All Documentation

900672

Sigma-Aldrich

Methoxy poly(ethylene glycol)-block-poly(ε-caprolactone)

5k-10k

Synonyme(s) :

mPEG-b-PCL, mPEG-PCL

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(2)

About This Item

Formule linéaire :
CH3O(CH2CH2O)n(COCH2CH2CH2CH2CH2O)mH
Code UNSPSC :
51171641
Nomenclature NACRES :
NA.23

Niveau de qualité

100

Forme

powder

Température de transition

Tm 61-65 °C

Température de stockage

2-8°C

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Application

Biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block. These materials have been used as a block copolymer surfactant as well as in control release and nanoparticle formulation for drug delivery applications. Well-defined materials with varying properties can be prepared by controlling the relative length of each polymer block. Hydroxyl termination allows for facile further chemical modification of these materials.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Xu Wen Ng et al.
Journal of pharmaceutical sciences, 103(11), 3631-3640 (2014-09-17)
Despite the success that drug-eluting stents (DESs) have achieved for minimizing in-stent restenosis (ISR), the antirestenotic agents used in DES have been implicated in delayed endothelial healing and impairment of endothelial functions. Cenderitide (CD-NP) is a novel antiproliferation chimeric peptide
On the mechanism of formation of vesicles from poly(ethylene oxide)-block-poly(caprolactone) copolymers.
Adams DJ, et al.
Soft Matter, 5, 3086-3096 (2009)
Xu Wen Ng et al.
Drug delivery and translational research, 5(5), 469-479 (2015-06-24)
Timolol maleate (TM) has been used for many years for the reduction of intraocular pressure (IOP) in glaucoma patients. However, the topical mode of administration (eyedrops) is far from optimal because of the issues of low bioavailability, high drug wastage
Simple solvothermalsynthesis of hydrophobic magnetic monodispersed Fe3O4 nanoparticles.
Liu J, et al.
Mat. Res. Bul., 48(2), 416-421 (2013)
Bhuvana S Doddapaneni et al.
Journal of controlled release : official journal of the Controlled Release Society, 220(Pt A), 503-514 (2015-11-19)
Metastatic melanoma has a high mortality rate due to lymphatic progression of the disease. Current treatment is surgery followed by radiation and intravenous chemotherapy. However, drawbacks for current chemotherapeutics lie in the fact that they develop resistance and do not
Afficher tous les articles scientifiques apparentés

Articles

Polymersomes for Drug Delivery

The development of drugs that target specific locations within the human body remains one of the greatest challenges in biomedicine today.

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique