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762881

Sigma-Aldrich

Poly(N-isopropylacrylamide-co-butylacrylate)

butylacrylate 12 mol %, average Mn 30,000

Synonyme(s) :

NIPAM, polyNIPAM, polyNIPAM-BA

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About This Item

Formule linéaire :
(C6H11NO)m(C7H12O2)n
Code UNSPSC :
12162002
Nomenclature NACRES :
NA.23

Forme

solid

Ratio alimentaire

NIPAM:BA 8:1

Poids mol.

average Mn 30,000

Composition

butylacrylate, 12 mol %

Température de transition

LCST 14-16 °C

PDI

1.51

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Catégories apparentées

Description générale

Random copolymer of N-isopropylacrylamide with 12 mole % butylacrylate. This copolymer shows LCST at 15 C (lower temperature than PolyNIPAM).

Application

Thermosensitive polymer; can be used to form a hydrogel. Aqueous polymer solution undergoes a phase transition from a soluble to an insoluble state when the temperature is raised to ca. 15 °C.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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A Gutowska et al.
Journal of biomedical materials research, 29(7), 811-821 (1995-07-01)
Biomer/poly(N-isopropylacrylamide)/[poly(NiPAAm)] thermosensitive polymer blends were prepared and their application as heparin-releasing polymer coatings for the prevention of surface-induced thrombosis was examined. The advantage of using poly (NiPAAm)-based coatings as heparin-releasing polymers is based on the unique temperature-dependent swelling of these
G Chen et al.
Nature, 373(6509), 49-52 (1995-01-05)
There are many potential applications of 'intelligent' aqueous polymer systems in medicine, biotechnology, industry and in environmental problems. Many of these polymer systems undergo reversible phase transitions--for example, abrupt changes in volume--in response to external stimuli such as temperature, pH

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By altering the physicochemical properties, smart or intelligent drug delivery systems can be designed to deliver therapeutic molecules on-demand. Learn more about the application of stimuli-responsive materials in drug delivery.

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