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  • Focusing on cardiovascular disease in type 2 diabetes mellitus: an introduction to bromocriptine QR.

Focusing on cardiovascular disease in type 2 diabetes mellitus: an introduction to bromocriptine QR.

Postgraduate medicine (2012-10-26)
David S Bell
ABSTRACT

Cardiovascular risk reduction is a key priority in patients with diabetes. The relationship between glycemic control and macrovascular outcomes, such as the benefit of intensive glucose control and the importance of postprandial or fasting blood glucose, is still under debate. A number of pharmacologic options are available to treat type 2 diabetes mellitus and these options have differing evidence for their cardiovascular safety. In this article, the novel agent bromocriptine quick release is discussed. Recently approved, this once-daily treatment provides glycemic control as monotherapy or in combination with other antihyperglycemic medications and has been shown in a prospective phase 3 safety study to not increase cardiovascular risk. Therefore, bromocriptine quick release increases the range of options available to treat patients with type 2 diabetes mellitus without increasing cardiovascular risk.

MATERIALS
Product Number
Brand
Product Description

Bromocriptine mesilate for system suitability, European Pharmacopoeia (EP) Reference Standard
Sigma-Aldrich
2-Bromo-α-ergocryptine methanesulfonate salt, solid