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E6375

Sigma-Aldrich

Estriol 3-sulfate sodium salt

≥98% (TLC)

Synonym(s):

1,3,5(10)-Estratriene-3,16α,17β-triol 3-sulfate, 3,16α,17β-Trihydroxy-1,3,5(10)-estratriene 3-sulfate

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About This Item

Linear Formula:
C18H23O6SNa
CAS Number:
5150-64-1
Molecular Weight:
390.43
MDL number:
MFCD00056547
UNSPSC Code:
12171500
PubChem Substance ID:
24894625
NACRES:
NA.47

Quality Level

200

Assay

≥98% (TLC)

form

powder

contains

~30% methylglucamine as stabilizer

solubility

methanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow

application(s)

diagnostic assay manufacturing
hematology
histology

shipped in

ambient

storage temp.

room temp

SMILES string

[Na].[H][C@]12CC[C@]3(C)[C@@H](O)[C@H](O)C[C@@]3([H])[C@]1([H])CCc4cc(OS(O)(=O)=O)ccc24

InChI

1S/C18H24O6S.Na.H/c1-18-7-6-13-12-5-3-11(24-25(21,22)23)8-10(12)2-4-14(13)15(18)9-16(19)17(18)20;;/h3,5,8,13-17,19-20H,2,4,6-7,9H2,1H3,(H,21,22,23);;/t13-,14-,15+,16-,17+,18+;;/m1../s1

InChI key

NGMCHEUPKPRHNC-XZEIGEQDSA-N

Related Categories

Packaging

Package size based on steroid content

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H351

Precautionary Statements

P281

Hazard Classifications

Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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T Tanaka et al.
Steroids, 63(10), 516-522 (1998-11-04)
A facile and sensitive chemiluminescence enzyme-linked immunosorbent assay (ELISA) of estriol 3-sulfate using a bridge-heterologous system was established. 6 alpha-Hydroxyestriol 3-sulfate 6-hemisuccinate was synthesized as a novel hapten. Antisera were raised in male guinea-pigs against 6 alpha-hydroxyestriol 3-sulfate 6-hemisuccinate-bovine serum
T Tanaka et al.
Steroids, 46(1), 649-657 (1985-07-01)
A highly specific anti-estriol 3-sulfate antiserum was treated with 50% ammonium sulfate, and the crude globulin fraction was coupled to CNBr-activated Sepharose-4B. Addition of 0.1M Tris-HC1 buffer (pH 8.3) containing 0.1M glutamine to the solution of antigen-antibody enabled assaying without
N Tagawa et al.
Biological & pharmaceutical bulletin, 21(11), 1211-1214 (1998-12-16)
A method to prevent co-elution of steroid sulfates with proteins in serum from the pre-column in column-switching HPLC was developed. The pre-column, a polymer-coated mixed function column, was used for ion-pair chromatography with 5 mM tetra-n-butylammonium (TBA) ion. As steroid
U Raju et al.
The Journal of clinical endocrinology and metabolism, 53(4), 847-851 (1981-10-01)
The high concentration of estriol-3-sulfate (E3-3S) in human breast cyst fluid has been confirmed in 14 women with multiple cysts. The concentrations of E3-3S found in individual cysts drained within a short time span from the same patient were variable
C Gelly et al.
Journal of steroid biochemistry, 24(1), 357-359 (1986-01-01)
The levels of progesterone receptors (PR [cytosol (Cy) and nuclear (N)] and estrogen receptors (ER) [cytosol and nuclear; occupied and unoccupied specific binding sites] were evaluated in the MCF-7 cancer cell line incubated with estriol (E3), estriol-3-sulfate (E3-3-S) or estriol-17-sulfate
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