G11608
Guanidineacetic acid
99%
Synonym(s):
N-Amidinoglycine, N-Guanylglycine, Glycocyamine
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Assay
99%
mp
300 °C (lit.)
SMILES string
NC(=N)NCC(O)=O
InChI
1S/C3H7N3O2/c4-3(5)6-1-2(7)8/h1H2,(H,7,8)(H4,4,5,6)
InChI key
BPMFZUMJYQTVII-UHFFFAOYSA-N
Related Categories
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Pediatric research, 36(3), 409-413 (1994-09-01)
In a patient with extrapyramidal movement disorder and extremely low creatinine concentrations in serum and urine, in vivo proton magnetic resonance spectroscopy disclosed a generalized depletion of creatinine in the brain. Oral substitution of arginine, a substrate for creatine synthesis
Orphanet journal of rare diseases, 7, 96-96 (2012-12-14)
A population of patients with unexplained neurological symptoms from six major French university hospitals was screened over a 28-month period for primary creatine disorder (PCD). Urine guanidinoacetate (GAA) and creatine:creatinine ratios were measured in a cohort of 6,353 subjects to
Molecular genetics and metabolism, 106(1), 48-54 (2012-03-06)
Arginine:glycineamidinotransferase (AGAT/GATM) deficiency has been described in 9 patients across 4 families. Here we describe the clinical outcome and response to creatine supplementation in a patient of the second family affected with AGAT deficiency-a 9-year-old girl. Delayed motor milestones were
Heart (British Cardiac Society), 97(15), 1222-1227 (2011-05-12)
Homoarginine is an amino acid which may play a role in nitric oxide and energy metabolism. Low homoarginine concentrations have previously been linked to increased mortality, but the underlying mechanisms remain unknown. To investigate whether serum homoarginine concentrations are associated
Clinica chimica acta; international journal of clinical chemistry, 348(1-2), 155-161 (2004-09-17)
A new gas chromatography-mass spectrometry method for routine quantification of urine creatine and guanidinoacetic acid (GAA) has been developed to provide a fast, reliable and inexpensive metabolic screening. Our method uses a two-step derivatization procedure which involves a reaction with
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