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GE45152105050250

SpeedBeads magnetic carboxylate modified particles

Cytiva 45152105050250, 1 μm avg. part. size, suspension (5% Solids)

Synonym(s):

SpeedBeads

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.56

ligand

(carboxylate modified particles)

form

suspension (5% Solids)

packaging

pkg of 15 mL

manufacturer/tradename

Cytiva 45152105050250

concentration

50 mg/mL

avg. part. size

1 μm

shipped in

wet ice

storage temp.

2-8°C

General description

Sera-Mag™ SpeedBeads and Sera-Mag™ Carboxylate-Modified Magnetic Particles combine a fast magnetic response time and high binding capacity with a large surface area, high sensitivity, stability, physical integrity, and fast reaction kinetics. Covalent coupling of biomolecules such as proteins and nucleic acids to carboxyl groups on the surface is easily accomplished using our standard coupling technology. The core of the particle is made by a free radical emulsion polymerization of styrene and acid monomer. One (Sera-Mag™) or two (Sera-Mag™ SpeedBeads) layers of magnetite are then coated onto this core, while the surface is modified to minimize non-specific binding of proteins.

Application

Sera-Mag™ SpeedBeads and Sera-Mag™ Carboxylate-Modified Magnetic Particles typical application uses include sample preparation, proteomics, nucleic acid isolation, and immunoassay applications.

Features and Benefits

Sera-Mag™ SpeedBeads and Sera-Mag™ Carboxylate-Modified Magnetic Particles allow convenient covalent coupling of target molecules.

  • Carboxylic groups on the surface permit easy covalent coupling to biomolecules of interest using convenient carbodiimide chemistry.
  • Different levels of hydrophobicity/hydrophilicity available.
  • Available in Sera-Mag™ SpeedBeads and original Sera-Mag™ versions.
  • Excellent sensitivity and low nonspecific binding for greater accuracy.
  • Fast Magnetic Response Times and Stable Physical Integrity

Storage and Stability

4 °C

Analysis Note

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Legal Information

Sera-Mag is a trademark of Cytiva

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Jan Leipert et al.
Lab on a chip, 19(20), 3490-3498 (2019-09-19)
While LC-MS-based proteomics with high nanograms to micrograms of total protein has become routine, the analysis of samples derived from low cell numbers is challenged by factors such as sample losses, or difficulties encountered with the manual manipulation of small
Magdalena Surman et al.
International journal of molecular sciences, 21(8) (2020-04-26)
Cutaneous melanoma (CM) is an aggressive type of skin cancer for which effective biomarkers are still needed. Recently, the protein content of extracellular vesicles (ectosomes and exosomes) became increasingly investigated in terms of its functional role in CM and as
Georg Michlits et al.
Nature methods, 14(12), 1191-1197 (2017-10-19)
Pooled CRISPR screens are a powerful tool for assessments of gene function. However, conventional analysis is based exclusively on the relative abundance of integrated single guide RNAs (sgRNAs) between populations, which does not discern distinct phenotypes and editing outcomes generated

Protocols

Preactivated Magnetic Beads for Affinity Chromatography

Covalent coupling of antibodies, aptamers, and proteins with a NHS Mag Sepharose, Sera-Mag Carboxylate-Modified, Sera-Mag SpeedBeads Carboxylate-Modified from Cytiva.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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