C8863

7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine

≥98% (HPLC)

• Empirical Formula (Hill Notation): C₂₃H₂₂N₄O
• CAS Number: 213743-31-8
• Molecular Weight: 370.45
• NACRES: NA.77
• PubChem Substance ID: 24278409
• UNSPSC Code: 12352116
• MDL number: MFCD04974490
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white
• solubility: DMSO: soluble 17 mg/mL at ≤60 °C
• storage temp.: 2-8°C
• SMILES string: Nc1ncnc2n(cc(-c3ccc(Oc4ccccc4)cc3)c12)C5CCCC5
• InChI: 1S/C23H22N4O/c24-22-21-20(14-27(17-6-4-5-7-17)23(21)26-15-25-22)16-10-12-19(13-11-16)28-18-8-2-1-3-9-18/h1-3,8-15,17H,4-7H2,(H2,24,25,26)
• InChI key: FMETVQKSDIOGPX-UHFFFAOYSA-N
• Gene Information: human ... KDR(3791), LCK(3932), TEK(7010)

Description

Biochem/physiol Actions

A potent and selective pyrrolo[2,3-d]pyrimidine Lck inhibitor.

Potent and selective inhibitor of Lck, a src family tyrosine kinase.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)