M9557

Anti-Macrophage Inflammatory Protein-3β antibody produced in goat

affinity isolated antibody, lyophilized powder

• Synonym(s): Anti-MIP-3β
• MDL number: MFCD02096844
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: goat
• Quality Level: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: mouse
• technique(s): immunocytochemistry: 5-15 μg/mL; neutralization: 0.8-4 μg/mL; western blot: 0.1-0.2 μg/mL
• UniProt accession no.: O70460
• storage temp.: −20°C
• Gene Information: mouse ... Ccl19(24047)

Description

General description

The antibody neutralizes the biological activity of recombinant mouse MIP-3β. Using 50 times more, the antibody will neutralize the biological activity of recombinant human MIP-3β. The antibody shows 5% cross-reactivity with recombinant human MIP-3β.

Immunogen

Recombinant mouse MIP-3β, expressed in Escherichia coli.

Biochem/physiol Actions

Macrophage Inflammatory Protein-3β is a chemokine that facilitates the migration of dendritic cells and antigen-presenting cells. It interacts with specific G protein-coupled seven-transmembrane domain chemokine receptor, CCR7 and promotes interactions between T cells and dendritic cells and migration of activated B cells to lymphoid tissues.

Physical form

Lyophilized from a 0.2 μm-filtered solution in phosphate-buffered saline containing carbohydrates.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable