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74294

Sigma-Aldrich

Chloroethane

≥99.8%

Synonym(s):

Ethyl chloride

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About This Item

Empirical Formula (Hill Notation):
C2H5Cl
CAS Number:
Molecular Weight:
64.51
Beilstein:
1730751
EC Number:
MDL number:
UNSPSC Code:
12142100
PubChem Substance ID:

vapor density

2.22 (vs air)

vapor pressure

19.2 psi ( 20 °C)

Assay

≥99.8%

impurities

≤0.02% water

bp

12.3 °C (lit.)

mp

−139 °C (lit.)

density

0.921 g/mL at 0-4 °C (lit.)

SMILES string

CCCl

InChI

1S/C2H5Cl/c1-2-3/h2H2,1H3

InChI key

HRYZWHHZPQKTII-UHFFFAOYSA-N

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General description

Chloroethane is a haloalkane used as an intermediate or as a solvent in organic synthesis. It has major applications in the production of tetraethyl lead, ethyl-cellulose, and an antiknock additive for gasoline. It is also used in cleaning and degreasing applications.

Application

Chloroethane can be used to prepare:
  • pyrido[1,2-a]pyrimidinone derivatives
  • 2H-perovskite compound [Me3NCH2CH3]CdCl3
  • benzo[cd]indol-2(1H)-ones derivatives as potent BRD4 inhibitors

Packaging

cylinder with 11.4 kg (net)

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Selective formation of chloroethane by the hydrochlorination of ethene using zinc catalysts
Conte M, et al.
J. Catal., 252(1), 23-29 (2007)
Reversible high temperature dielectric switching in a 2 H-perovskite compound:[Me 3 NCH 2 CH 3] CdCl 3
Sun D, et al.
CrystEngComm, 21(16), 2669-2674 (2019)
First discovery of novel pyrido [1,2-a] pyrimidinone mesoionic compounds as antibacterial agents
Liu D, et al.
Journal of Agricultural and Food Chemistry, 67(43), 11860-11866 (2019)
Design, synthesis and biological evaluation of benzo [cd] indol-2 (1H)-ones derivatives as BRD4 inhibitors
Feng Y, et al.
European Journal of Medicinal Chemistry, 152(16), 264-273 (2018)
Xi-Guang Wei et al.
The Journal of organic chemistry, 75(12), 4212-4217 (2010-05-21)
The enhanced reactivity exhibited by six pseudo-alpha-bases, RC[triple bond]CZ(-) (R = H and Cl; Z = O, S, and Se) in gas-phase E2 reactions with ethyl chloride was examined at the G2(+) level. It is found that anomalous reactivity is

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