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Sigma-Aldrich

5-Bromo-2′,3′-dideoxyuridine

99%

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About This Item

Empirical Formula (Hill Notation):
C9H11BrN2O4
CAS Number:
Molecular Weight:
291.10
MDL number:

Assay

99%

SMILES string

OC[C@@H]1CC[C@@H](O1)N2C=C(Br)C(=O)NC2=O

InChI

1S/C9H11BrN2O4/c10-6-3-12(9(15)11-8(6)14)7-2-1-5(4-13)16-7/h3,5,7,13H,1-2,4H2,(H,11,14,15)/t5-,7+/m0/s1

InChI key

MREZUWMZVPBIEE-CAHLUQPWSA-N

Application

Research tool for antiviral and anticancer studies.

Certificates of Analysis (COA)

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Andrzej Wojcik et al.
Journal of photochemistry and photobiology. B, Biology, 69(2), 139-144 (2003-03-14)
The role of 5-bromo-2'-deoxyuridine (BrdU) in the formation of sister chromatid exchanges (SCEs) in cells exposed to UV radiation was studied. Cells were unifilarily labelled (labelling of one strand of chromosomal DNA) with BrdU or biotin-16-2'-deoxyuridine (biotin-dU) and irradiated in
Ruben Guzman-Marin et al.
Sleep, 31(2), 167-175 (2008-02-16)
The dentate gyrus (DG) of the adult hippocampus contains progenitor cells, which have potential to differentiate into neurons. Previously we reported that 96 hours of total sleep deprivation reduces neurogenesis in the DG of adult rats. Loss of either non-rapid
Makoto Hayashi et al.
The EMBO journal, 26(5), 1327-1339 (2007-02-17)
DNA replication of eukaryotic chromosomes initiates at a number of discrete loci, called replication origins. Distribution and regulation of origins are important for complete duplication of the genome. Here, we determined locations of Orc1 and Mcm6, components of pre-replicative complex
H Kim et al.
Acta crystallographica. Section C, Crystal structure communications, 47 ( Pt 9), 1892-1895 (1991-09-15)
C9H11BrN2O4, Mr = 291.11, monoclinic, P2(1), a = 11.307 (1), b = 5.954 (1), c = 15.829 (2) A, beta = 93.25 (1) degree, V = 1063.90 A3, Z = 4, Dx = 1.82 g cm-3, lambda(Cu K alpha) =
Jean-Bernard Manent et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 25(19), 4755-4765 (2005-05-13)
Immature neurons express GABA and glutamate receptors before synapse formation, and both transmitters are released at an early developmental stage. We have now tested the hypothesis that the ongoing release of GABA and glutamate modulates neuronal migration. Using 5-bromo-2'-deoxyuridine labeling

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