SAV1
salvador homolog 1 (Drosophila)
Synonyms:
SAV, WW45, WWP4
Species:
Human SAV1 (60485), Mouse Sav1 (64010), Rat Sav1 (299116), chicken SAV1 (423578), dog SAV1 (480319), domestic cat SAV1 (101096154), naked mole-rat Sav1 (101726669), Horse SAV1 (100066557), sheep SAV1 (101104666), Domestic Rabbit SAV1 (100350937) ...More
UniProtKB ID:
Gene ID:
- Human(60485) Summary: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. [provided by RefSeq, Aug 2012]
- Mouse(64010) salvador homolog 1 (Drosophila)
- Rat(299116) salvador homolog 1 (Drosophila)
- chicken(423578) salvador homolog 1 (Drosophila)
- dog(480319) salvador homolog 1 (Drosophila)
- domestic cat(101096154) salvador homolog 1 (Drosophila)
- naked mole-rat(101726669) salvador homolog 1 (Drosophila)
- Horse(100066557) salvador homolog 1 (Drosophila)
- sheep(101104666) salvador homolog 1 (Drosophila)
- Domestic Rabbit(100350937) salvador homolog 1 (Drosophila)
- domestic guinea pig(100728249) salvador homolog 1 (Drosophila)
- Zebrafish(447821) salvador homolog 1 (Drosophila)
- cow(516557) salvador homolog 1 (Drosophila)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SAV1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-SAV1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti- SAV1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-SAV1 Antibody, clone 3A1.1, clone 3A1.1, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-Sav1 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, horse, human, mouse, pig, rabbit, rat
Application
western blot