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NELFB

negative elongation factor complex member B

Synonyms:
COBRA1, NELF-B
Species:
UniProtKB ID:
Gene ID:
  • Human(25920) Summary: NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]
  • Mouse(58202) negative elongation factor complex member B, Cobra1
  • Rat(311796) negative elongation factor complex member B
  • Zebrafish(393137) negative elongation factor complex member B
  • naked mole-rat(101711901) negative elongation factor complex member B
  • cow(512799) negative elongation factor complex member B
  • domestic guinea pig(100714039) negative elongation factor complex member B

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esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human NELFB,
Species
human