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Merck

MATK

megakaryocyte-associated tyrosine kinase

Synonyms:
CHK, CTK, HHYLTK, HYL, HYLTK, Lsk
Species:
UniProtKB ID:
Gene ID:
  • Human(4145) Summary: The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(17179) megakaryocyte-associated tyrosine kinase
  • Rat(60450) megakaryocyte-associated tyrosine kinase
  • cow(504668) megakaryocyte-associated tyrosine kinase
  • sheep(101117161) megakaryocyte-associated tyrosine kinase
  • domestic guinea pig(100729756) megakaryocyte-associated tyrosine kinase
  • Thale Cress(844797) maturase K
  • Zebrafish(567405) megakaryocyte-associated tyrosine kinase
  • chicken(769076) megakaryocyte-associated tyrosine kinase
  • dog(611999) megakaryocyte-associated tyrosine kinase
  • domestic cat(101099024) megakaryocyte-associated tyrosine kinase
  • naked mole-rat(101718779) megakaryocyte-associated tyrosine kinase

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ELISA

Product Number
Description
Species
Phosphotyrosine MATK / Megakaryocyte-associated Tyrosine-protein Kinase ELISA Kit, ,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MATK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-MATK Antibody, clone 9D7, ascites fluid, clone 9D7, from mouse,
Species Reactivity
human
Application
flow cytometry
western blot
Anti-MATK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Monoclonal Anti-MATK, (C-terminal) antibody produced in mouse, clone 2C5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MATK,
Species
human