GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
Synonyms:
ECA5
Species:
Human GABRB3 (2562), Mouse Gabrb3 (14402), Rat Gabrb3 (24922), Zebrafish gabrb3 (566922), chicken GABRB3 (396290), Horse GABRB3 (100050803), cow GABRB3 (529593), dog GABRB3 (606913), sheep GABRB3 (101114905), domestic cat GABRB3 (100286790) ...More
UniProtKB ID:
Gene ID:
- Human(2562) Summary: This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. This gene may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2013]
- Mouse(14402) gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
- Rat(24922) gamma-aminobutyric acid (GABA) A receptor, beta 3
- Zebrafish(566922) gamma-aminobutyric acid (GABA) A receptor, beta 3
- chicken(396290) gamma-aminobutyric acid (GABA) A receptor, beta 3
- Horse(100050803) gamma-aminobutyric acid (GABA) A receptor, beta 3
- cow(529593) gamma-aminobutyric acid (GABA) A receptor, beta 3
- dog(606913) gamma-aminobutyric acid (GABA) A receptor, beta 3
- sheep(101114905) gamma-aminobutyric acid (GABA) A receptor, beta 3
- domestic cat(100286790) gamma-aminobutyric acid (GABA) A receptor, beta 3
- domestic guinea pig(100731340) gamma-aminobutyric acid (GABA) A receptor, beta 3
- naked mole-rat(101711687) gamma-aminobutyric acid (GABA) A receptor, beta 3
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Small Molecule - Agonist
Small Molecule - Allosteric Modulator
Product Number
Description
Species
(±)Thiopental solution, 1.0 mg/mL in methanol, analytical standard, for drug analysis,
Species
human
Butalbital solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-GABRB3 antibody produced in mouse, clone S87-25, 1 mg/mL, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
western blot
western blot
Anti-GABRB3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
immunohistochemistry
immunohistochemistry
Anti-GABRB3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Small Molecule - Ligand
esiRNA
Product Number
Description
Species