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Merck

CFP

complement factor properdin

Synonyms:
BFD, PFC, PFD, PROPERDIN
Species:
UniProtKB ID:
Gene ID:
  • Human(5199) Summary: This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Feb 2009]
  • Mouse(18636) complement factor properdin
  • Rat(299314) complement factor properdin
  • Zebrafish(556399) complement factor properdin
  • domestic cat(101090086) complement factor properdin
  • dog(491859) complement factor properdin
  • Domestic Rabbit(100340696) complement factor properdin
  • sheep(101114678) complement factor properdin
  • cow(539605) complement factor properdin
  • Horse(100051317) complement factor properdin
  • naked mole-rat(101724230) complement factor properdin
  • domestic guinea pig(100728194) complement factor properdin

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Properdin/CFP Antibody, clone 1K9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, rat
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-Properdin Antibody, clone 6E11A4, clone 6E11A4, from mouse,
Species Reactivity
baboon, canine, human, rabbit
Application
ELISA
immunohistochemistry

western blot
Anti-Properdin Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, nonhuman primates, rat
Application
western blot
Anti-Properdin Antibody, clone 6E9E6, clone 6E9E6, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-Properdin Antibody, clone 3A3E1, clone 3A3E1, from mouse,
Species Reactivity
baboon, canine, human, rabbit
Application
ELISA
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CFP,
Species
human