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Merck

ARHGDIB

Rho GDP dissociation inhibitor (GDI) beta

Synonyms:
D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2
Species:
Human ARHGDIB (397), Mouse Arhgdib (11857), Rat Arhgdib (362456), sheep ARHGDIB (101106069), domestic guinea pig Arhgdib (100735099), naked mole-rat Arhgdib (101717849), chicken ARHGDIB (417941), dog ARHGDIB (486666), domestic cat ARHGDIB (101097252), cow ARHGDIB (327676)
UniProtKB ID:
P52566, B5BU79
Gene ID:
  • Human(397) Summary: Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]
  • Mouse(11857) Rho, GDP dissociation inhibitor (GDI) beta
  • Rat(362456) Rho, GDP dissociation inhibitor (GDI) beta
  • sheep(101106069) Rho GDP dissociation inhibitor (GDI) beta
  • domestic guinea pig(100735099) Rho GDP dissociation inhibitor (GDI) beta
  • naked mole-rat(101717849) Rho GDP dissociation inhibitor (GDI) beta
  • chicken(417941) Rho GDP dissociation inhibitor (GDI) beta
  • dog(486666) Rho GDP dissociation inhibitor (GDI) beta
  • domestic cat(101097252) Rho GDP dissociation inhibitor (GDI) beta
  • cow(327676) Rho GDP dissociation inhibitor (GDI) beta

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB1410756
Anti-ARHGDIB antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
HPA051235
Anti-ARHGDIB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
SAB1405484
Anti-ARHGDIB antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
EMU031071
MISSION® esiRNA, targeting mouse Arhgdib,
Species
mouse