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Merck

ADRBK1

adrenergic, beta, receptor kinase 1

Synonyms:
BARK1, BETA-ARK1, GRK2
Species:
UniProtKB ID:
Gene ID:
  • Human(156) Summary: The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008]
  • Mouse(110355) adrenergic receptor kinase, beta 1
  • Rat(25238) adrenergic, beta, receptor kinase 1
  • naked mole-rat(101708906) adrenergic, beta, receptor kinase 1
  • domestic cat(101101082) adrenergic, beta, receptor kinase 1
  • cow(282682) adrenergic, beta, receptor kinase 1
  • dog(483701) adrenergic, beta, receptor kinase 1
  • domestic guinea pig(100732560) adrenergic, beta, receptor kinase 1
  • sheep(101108265) adrenergic, beta, receptor kinase 1
  • chicken(426000) adrenergic, beta, receptor kinase 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-GRK2 (pSer685) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-GRK2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-GRK2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-GRK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-ADRBK1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
GRK2, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human GRK2,
Species
human
MISSION® esiRNA, targeting mouse Adrbk1,
Species
mouse