- Testing meningococcal vaccines for mitogenicity and superantigenicity.
Testing meningococcal vaccines for mitogenicity and superantigenicity.
Methods in molecular medicine (2001-01-01)
A A Delvig, J H Robinson, L Wetzler
PMID21336757
ABSTRACT
Proteins with intrinsic mitogenic properties are widely represented in prokaryotes, such as in different Streptococcus species (1-3), Candida albicans (4), and Eikenella corrodens (5). Specifically, several bacterial porins of Escherichia coli, Shigella dysenteriae, Salmonella typhimurium, Fusobacterium nucleatum, and pathogenic Neisseria species have been shown to induce nonspecific proliferation of lymphocytes (6-12).
MATERIALS
Product Number
Brand
Product Description
Sigma-Aldrich
Ethylenediaminetetraacetic acid, anhydrous, crystalline, BioReagent, suitable for cell culture
Sigma-Aldrich
HEPES solution, 1 M, pH 7.0-7.6, sterile-filtered, BioReagent, suitable for cell culture
Sigma-Aldrich
Concanavalin A from Canavalia ensiformis (Jack bean), Type IV-S, lyophilized powder, aseptically processed, BioReagent, suitable for cell culture