939692
Poly(glycerol sebacate) methacrylate
degree of methacrylation 20%, contains 150 ppm MEHQ as inhibitor
Synonym(s):
PGS-MA
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About This Item
Linear Formula:
[CH2CH(O2C4H5)CH2OOC(CH2)8COO]n
UNSPSC Code:
12352201
Recommended Products
Quality Level
form
(liquid/paste)
contains
150 ppm MEHQ as inhibitor
color
white/yellow
storage temp.
−20°C
General description
Poly(glycerol sebacate) methacrylate (PGS-MA) is a photopolymerizable biodegradable elastomer with tunable mechanical properites that can be used for bioprinting, tissue engineering, and regenerative medicine applications including cardiac, nerve, and muscle tissues. PGS is derived from the naturally occuring metabolites glycerol and sebacic acid, which have both been used for FDA approved biomedical applications. The polymer backbone contains ester bonds that can undergo hydrolytic degradation and can also be covalently crosslinked to form a 3D network at higher temperatures under vacuum. The addition of the methacrylate functional groups provides another mechanism of crosslinking via photopolymerization. The PGS-MA can be quickly and efficiently crosslinked under the exposure of UV and visible light in the presence of a photoinitiatior.
Application
- Soft tissue engineering such as blood vessels, cornea and nerve tissue
- Orthopedic implants and regenerative medicine application like muscle tissues
- Nanoparticle formulation and drug delivery systems
- Flexible wearable or implantable bioelectronic applications
Features and Benefits
- Flexible elastomer with tunable mechanical properties
- Higher reversible deformation properties
- Shape memory
- Bioresorbable polymer
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Description
Pricing
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Sens. 1
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Poly(Glycerol Sebacate) in Biomedical Applications?A Review of the Recent Literature
Vogt L, et al
Advanced Healthcare Materials, 10, 2002026-2002026 (2021)
Synthesis, Characterization and 3D Micro-Structuring via 2-Photon Polymerization of Poly(glycerol sebacate)-Methacrylate?An Elastomeric Degradable Polymer
Pashneh-Tala S, et al
Frontiers in physics, 6 (2018)
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