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Key Documents

937274

Sigma-Aldrich

Poly(propylene sulfide)

new

average Mw 15000

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About This Item

Linear Formula:
(C3H6S)n
CAS Number:
UNSPSC Code:
12352142

Agency

suitable for controlled release

Quality Level

form

viscous liquid

mol wt

average Mw 15000

color

colorless

application(s)

advanced drug delivery (tissue engineering, medical devices)

storage temp.

2-8°C

General description

Poly(propylene sulfide) (PPS) is a thermoplastic polymer that has shown potential for use in various biomedical applications due to its biocompatibility, biodegradability, and tunable mechanical and chemical properties.

Application

One promising application of PPS is in drug delivery. PPS nanoparticles can be synthesized and loaded with drugs, providing sustained release and targeted delivery to specific tissues or cells. PPS also has good stability in biological environments, which is important for maintaining drug efficacy during storage and delivery.



PPS has also been explored as a material for tissue engineering. Its biocompatibility and ability to be tailored for specific mechanical and chemical properties make it a potentially useful scaffold material for various tissue types, including bone and cartilage. PPS has also been shown to support cell attachment and growth in vitro.

In addition to drug delivery and tissue engineering, PPS has also been investigated for use in medical devices such as catheters and sutures. Its chemical resistance and low toxicity make it a potential alternative to traditional materials like silicone and nylon. Overall, PPS has shown promise for various biomedical applications, and ongoing research is exploring its potential in areas such as wound healing, cancer therapy, and regenerative medicine.

Features and Benefits

  • Biocompatible
  • Biodegradable
  • Tunable mechanical and chemical properties
  • Ideal for sustained release and targeted delivery
  • Chemically resisitant and low toxicity

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Extracellular matrix binding mixed micelles for drug delivery applications
O'Neil P N, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 137, 146-151 (2009)
Accelerated wound healing by injectable star poly(ethylene glycol)-b-poly(propylene sulfide) scaffolds loaded with poorly water-soluble drugs
Zhu S, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 282, 156-165 (2018)
In vivo targeting of dendritic cells in lymph nodes with poly(propylene sulfide) nanoparticles
Reddy T S, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 112, 26-34 (2006)

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