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HPLC Analysis of CYP3A Inhibitors on Ascentis® Express RP-Amide

HPLC Analysis of CYP3A Inhibitors on Ascentis® Express RP-Amide application for HPLC

CONDITIONS

column

Ascentis Express RP-Amide, 10 cm x 2.1 mm I.D., 2.7 μm particles (53913-U)

mobile phase

[A] 20 mM ammonium formate in 50:50 (v/v) water:acetonitrile

flow rate

0.6 mL/min

column temp.

35 °C

detector

ESI(+), m/z 100-600

injection

1 μL

Description

Analysis Note

This application demonstrates the suitability of the Ascentis Express RP Amide for the analysis of CYP3A Inhibitors.

Legal Information

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany