pH Effects on Electrospray Ionization Efficiency.

pH Effects on Electrospray Ionization Efficiency.

Journal of the American Society for Mass Spectrometry (2016-12-15)

Jaanus Liigand, Asko Laaniste, Anneli Kruve

ABSTRACT

Electrospray ionization efficiency is known to be affected by mobile phase composition. In this paper, a detailed study of analyte ionization efficiency dependence on mobile phase pH is presented. The pH effect was studied on 28 compounds with different chemical properties. Neither pK

MATERIALS

Product Number

Brand

Product Description

D0787

Sigma-Aldrich

3-(Dimethylamino)benzoic acid, ≥97% (HPLC)

CDS001202

Sigma-Aldrich

3-Methoxy-N,N-dimethylaniline, Aldrich^CPR