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EMU011001

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Spry2

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CTGCTGCTGCTGATGGAATAATCCGAGTGCAGCCTAAATCGGAGCTCAAGCCTGGTGACGTTAAGCCACTGAGCAAGGATGATTTGGGTCTGCATGCCTACAGGTGTGAGGACTGCGGCAAGTGCAAGTGTAAGGAGTGCACCTACCCGAGGCCCCTGCCGTCGGACTGGATCTGTGACAAGCAGTGCCTCTGCTCAGCCCAGAACGTCATTGACTATGGGACTTGTGTGTGCTGTGTGAAAGGTCTCTTCTATCACTGCTCCAATGACGATGAGGACAATTGTGCTGACAACCCGTGCTCTTGCAGCCAGTCCCATTGTTGTACGCGATGGTCAGCGATGGGAGTCATGTCTCTCTTTTTGCCTTGTTTATGGTGTTACCTTCCAGCCAAGGGTTGCCTTAAATTGTGCCAGGGGTGTT

Ensembl | mouse accession no.

ENSMUSG00000022114

NCBI accession no.

NM_011897

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... SPRY2(24064) , Spry2(24064)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Jun-Ho Ahn et al.
Biomolecules & therapeutics, 23(4), 320-326 (2015-07-15)
The clinical benefits of oncogenic BRAF inhibitor therapies are limited by the emergence of drug resistance. In this study, we investigated the role of a negative regulator of the MAPK pathway, Spry2, in acquired resistance using BRAF inhibitor-resistant derivatives of

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