8.41359
Triisopropylsilane
for synthesis
Synonym(s):
Triisopropylsilane
About This Item
Recommended Products
Quality Level
Assay
≥98.0% (GC)
form
liquid
bp
84-85 °C/46.7 hPa
transition temp
flash point 35 °C
density
0.77 g/cm3 at 20 °C
storage temp.
2-30°C
InChI
1S/C9H22Si/c1-7(2)10(8(3)4)9(5)6/h7-10H,1-6H3
InChI key
YDJXDYKQMRNUSA-UHFFFAOYSA-N
Application
- Total synthesis of diazaquinomycins H and J using double Knorr cyclization: This paper covers the first total synthesis of diazaquinomycins, highlighting the role of triisopropylsilane in enhancing reaction efficiency (Prior & Sun, 2019).
- Reduction of cysteine‐S‐protecting groups by triisopropylsilane: An in-depth look at the chemical properties of triisopropylsilane, emphasizing its effectiveness in peptide synthesis processes (Ste. Marie & Hondal, 2018).
Analysis Note
Density (d 20 °C/ 4 °C): 0.765 - 0.772
Identity (IR): passes test
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Flam. Liq. 3
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point(F)
100.4 °F - closed cup
Flash Point(C)
38 °C - closed cup
Certificates of Analysis (COA)
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Protocols
Fmoc resin cleavage and deprotection are crucial steps for peptide synthesis, yielding the desired peptide after resin detachment.
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