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Merck

SORBS2

sorbin and SH3 domain containing 2

Synonyms:
ARGBP2, PRO0618
Species:
Human SORBS2 (8470), Mouse Sorbs2 (234214), Rat Sorbs2 (114901), naked mole-rat Sorbs2 (101713243), domestic guinea pig Sorbs2 (100724374), Domestic Rabbit SORBS2 (100344295), sheep SORBS2 (101114586), cow SORBS2 (614391), domestic cat SORBS2 (101093349), Horse SORBS2 (100050682) ...More
UniProtKB ID:
O94875, A6NEK9, B3KPQ7, B7Z1G5, B7Z3X6, C9JKV9, D3DP62, D3DP63
Gene ID:
  • Human(8470) Summary: Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(234214) sorbin and SH3 domain containing 2
  • Rat(114901) sorbin and SH3 domain containing 2
  • naked mole-rat(101713243) sorbin and SH3 domain containing 2
  • domestic guinea pig(100724374) sorbin and SH3 domain containing 2
  • Domestic Rabbit(100344295) sorbin and SH3 domain containing 2
  • sheep(101114586) sorbin and SH3 domain containing 2
  • cow(614391) sorbin and SH3 domain containing 2
  • domestic cat(101093349) sorbin and SH3 domain containing 2
  • Horse(100050682) sorbin and SH3 domain containing 2
  • dog(482906) sorbin and SH3 domain containing 2
  • chicken(422719) sorbin and SH3 domain containing 2

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Antibodies

Product Number
Description
Species Reactivity
Application
HPA036754
Anti-SORBS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
SAB1406674
Anti-SORBS2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
HPA036755
Anti-SORBS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
SAB4200183
Anti-SORBS2 antibody,Mouse monoclonal, clone S5C, purified from hybridoma cell culture,
Species Reactivity
canine, hamster, human, mouse, rat
Application
immunocytochemistry
immunoprecipitation (IP)
western blot
SAB1306615
ANTI-ARGBP2(N-TERMINAL) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
immunofluorescence
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EHU070391
MISSION® esiRNA, targeting human SORBS2,
Species
human