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Merck

RTEL1

regulator of telomere elongation helicase 1

Synonyms:
C20orf41, DKCB5, NHL, RTEL, bK3184A7.3
Species:
UniProtKB ID:
Gene ID:
  • Human(51750) Summary: In mice, inactivation of the Rtel (regulator of telomere length) gene has been shown to cause chromosome breaks, fusions, and telomere loss. In addition, Rtel is required for telomere elongation. Therefore, the mouse Rtel gene regulates chromosome stability and telomere length. This gene is the human ortholog of the mouse Rtel gene, so its protein product may play similar roles in humans. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, decoy (TNFRSF6B), generates a non-coding transcript. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(269400) regulator of telomere elongation helicase 1
  • Rat(362288) regulator of telomere elongation helicase 1
  • Zebrafish(503732) regulator of telomere elongation helicase 1
  • naked mole-rat(101711246) regulator of telomere elongation helicase 1
  • domestic guinea pig(100716322) regulator of telomere elongation helicase 1
  • chicken(419262) regulator of telomere elongation helicase 1
  • cow(505721) regulator of telomere elongation helicase 1
  • domestic cat(101095970) regulator of telomere elongation helicase 1
  • dog(485976) regulator of telomere elongation helicase 1
  • sheep(101117606) regulator of telomere elongation helicase 1

Custom & Knockdown Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-RTEL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-RTEL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-RTEL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human RTEL1, RTEL1-TNFRSF6B,
Species
human