PRG2
proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
Synonyms:
BMPG, MBP, MBP1
Species:
UniProtKB ID:
Gene ID:
- Human(5553) Summary: The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
- Mouse(19074) proteoglycan 2, bone marrow
- Rat(58826) proteoglycan 2, bone marrow
- Horse(100062803) proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PRG2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-Eosinophil Major Basic Protein Antibody, clone BMK13, clone BMK13, Chemicon®, from mouse,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
esiRNA
Product Number
Description
Species