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Merck

INHBA

inhibin, beta A

Synonyms:
EDF, FRP
Species:
UniProtKB ID:
Gene ID:
  • Human(3624) Summary: The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome. [provided by RefSeq, Jul 2008]
  • Mouse(16323) inhibin beta-A
  • Rat(29200) inhibin beta-A
  • domestic cat(493853) inhibin, beta A
  • chicken(396361) inhibin, beta A
  • cow(281867) inhibin, beta A
  • naked mole-rat(101704279) inhibin, beta A
  • domestic guinea pig(100720616) inhibin, beta A
  • sheep(443524) inhibin, beta A
  • Goat(100860960) inhibin, beta A
  • Horse(100034076) inhibin, beta A
  • dog(483245) inhibin, beta A

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ELISA

Product Number
Description
Species
Mouse INHBA / Inhba Protein ELISA Kit, ,
Species
mouse
Rat Inhba / Inhibin Beta A chain ELISA Kit, for serum, plasma and cell culture supernatants,
Species
rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-INHBA (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, goat, horse, human, mouse, pig, rabbit, rat, sheep
Application
western blot
Anti-INHBA antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-Activin A antibody produced in goat, affinity isolated antibody, lyophilized powder,
Species Reactivity
human
Application
ELISA
immunohistochemistry

neutralization

western blot
Anti-INHBA Rabbit pAb, liquid, Calbiochem®,
Species Reactivity
human, mouse
Application
Anti-Inhibin beta A (INHBA) Antibody, clone 1X6N9, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot

Proteins

Product Number
Description
Species
Activin A active human, Animal-component free, recombinant, expressed in Nicotiana, >97% (SDS-PAGE),
Species
human
Activin A human, ≥95% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, lyophilized powder, suitable for cell culture,
Species
human
Activin A human, recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC), suitable for cell culture,
Species
mouse, rat, human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human INHBA,
Species
human
MISSION® esiRNA, targeting mouse Inhba,
Species
mouse