- First universal pharmacophore model for hERG1 K
First universal pharmacophore model for hERG1 K
Journal of molecular graphics & modelling (2017-05-13)
Serdar Durdagi, Ismail Erol, Ramin Ekhteiari Salmas, Matthew Patterson, Sergei Y Noskov
PMID28499268
ZUSAMMENFASSUNG
The intra-cavitary drug blockade of hERG1 channel has been extensively studied, both experimentally and theoretically. Structurally diverse ligands inadvertently block the hERG1 K
MATERIALIEN