Direkt zum Inhalt
Merck
  • gem-Difluorination of 2,2-diaryl-1,3-dithiolanes by Selectfluor and pyridinium polyhydrogen fluoride.

gem-Difluorination of 2,2-diaryl-1,3-dithiolanes by Selectfluor and pyridinium polyhydrogen fluoride.

Chemical communications (Cambridge, England) (2005-01-27)
V Prakash Reddy, Ramesh Alleti, Meher K Perambuduru, Urs Welz-Biermann, Herwig Buchholz, G K Surya Prakash
ZUSAMMENFASSUNG

2,2-diaryl-1,3-dithiolanes, readily obtainable from diaryl ketones, were transformed into the corresponding gem-difluoro compounds using a novel reagent combination involving Selectfluor and pyridinium polyhydrogen fluoride (PPHF) under mild conditions in moderate to good yields.

MATERIALIEN
Produktnummer
Marke
Produktbeschreibung

Sigma-Aldrich
Fluorwasserstoffpyridin, pyridine ~30 %, hydrogen fluoride ~70 %
Sigma-Aldrich
1,3-Dithiolan, 97%