- Occurrence of Tako-Tsubo cardiomyopathy in association with ingestion of serotonin/noradrenaline reuptake inhibitors.
Occurrence of Tako-Tsubo cardiomyopathy in association with ingestion of serotonin/noradrenaline reuptake inhibitors.
Heart, lung & circulation (2012-01-31)
Christopher J A Neil, Cher-Rin Chong, Thanh H Nguyen, John D Horowitz
PMID22285074
ZUSAMMENFASSUNG
Tako-Tsubo cardiomyopathy (TTC) occurs particularly in post-menopausal women, being precipitated in many cases by severe emotional stress. We describe six patients in whom TTC occurred in association with therapeutic ingestion or overdose of the serotonin/noradrenaline reuptake inhibitor venlafaxine, or its metabolite desvenlafaxine. Importantly, two of the six cases were not post-menopausal women. An increased risk of TTC may account for some of the reported cardiovascular adverse effects of venlafaxine and similar agents.
MATERIALIEN
Produktnummer
Marke
Produktbeschreibung
Supelco
O-Desmethylvenlafaxine solution, 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®