- One-pot multicomponent synthesis of two novel thiolactone scaffolds.
One-pot multicomponent synthesis of two novel thiolactone scaffolds.
Molecular diversity (2010-04-22)
B Beck, S Srivastava, K Khoury, E Herdtweck, Alexander Dömling
PMID20407923
ZUSAMMENFASSUNG
We designed two novel thiolactone scaffolds. Both scaffolds can be accessed by a convergent Ugi multicomponent reaction (MCR) and are, thus, amenable to library synthesis. Design, stereoselectivity, structures, full experimental details, and virtual libraries will be reported.
MATERIALIEN