- Bridgehead enolates and bridgehead alkenes in a welwistatin model series.
Bridgehead enolates and bridgehead alkenes in a welwistatin model series.
Chemical communications (Cambridge, England) (2009-03-05)
Valerie Boissel, Nigel S Simpkins, Gurdip Bhalay, Alexander J Blake, William Lewis
PMID19259600
ZUSAMMENFASSUNG
Bridgehead metallation is possible in a ketone having the welwistatin skeleton, and this facilitates installation of the isothiocyanate function present in the natural product, and also enables synthesis of remarkable bridgehead alkenes.