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A metathesis-based approach to the synthesis of furans.

Organic letters (2007-02-24)
Timothy J Donohoe, Lisa P Fishlock, Adam R Lacy, Panayiotis A Procopiou
ZUSAMMENFASSUNG

The enol ether-olefin ring-closing metathesis reaction has been employed to generate 2,3-dihydrofurans that are equipped with a leaving group. These substrates are at the correct oxidation state to undergo an acid-catalyzed aromatization, and this strategy has been utilized to provide a mild and rapid route (four steps) to a range of novel 2,5-disubstituted furans. [reaction: see text]

MATERIALIEN
Produktnummer
Marke
Produktbeschreibung

Sigma-Aldrich
2,3-Dihydrofuran, 99%