SRP8008

FTO mouse

recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE)

• Synonym(e): EC 1.14.11, FATSO, Fat mass and obesity-associated protein, Preadipocyte factor 1
• UNSPSC-Code: 12352200
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: mouse
• Rekombinant: expressed in E. coli
• Markierung: His tagged
• Assay: >90% (SDS-PAGE)
• Form: liquid
• Mol-Gew.: ~55 kDa by SDS-PAGE
• Verpackung: pkg of 10 μg
• Lagerbedingungen: avoid repeated freeze/thaw cycles
• Konzentration: ≥0.2 mg/mL
• Verunreinigungen: <1 EU/μg endotoxin, tested
• Farbe: clear
• UniProt-Hinterlegungsnummer: Q8BGW1
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: mouse ... Fto(26383)

Beschreibung

Allgemeine Beschreibung

FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ′fused toes′ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.

Physikalische Form

Solution in 55 mM TRIS-HCl, pH 8.2, containing 150 mM NaCl.

Sonstige Hinweise

Mouse FTO (aa 2-502) is fused at the N-terminus to a His-tag.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable