SRP6561

Cathepsin K Active human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

• Synonym(e): CTSK, CTSO, CTSO3
• UNSPSC-Code: 12352200
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: human
• Rekombinant: expressed in E. coli
• Assay: ≥90% (SDS-PAGE)
• Form: liquid
• Mol-Gew.: 23.5 kDa (115-329 aa)
• Verpackung: pkg of 5 μg; pkg of 50 μg
• Konzentration: 0.5 mg/mL
• Methode(n): activity assay: suitable
• Eignung: suitable for molecular biology
• UniProt-Hinterlegungsnummer: P43235
• Anwendung(en): life science and biopharma
• Versandbedingung: dry ice
• Lagertemp.: −70°C
• Angaben zum Gen: human ... CTSK(1513)

Beschreibung

Allgemeine Beschreibung

Cathepsin K is expressed as procathepsin K, which is the inactive proenzyme of cathepsin K. Cathepsin K is a lysosomal cysteine protease and part of the papain cysteine protease family. It is expressed in osteoclasts. The gene encoding this protein is localized on human chromosome 1q21.

Biochem./physiol. Wirkung

Cathepsin K has a role in bone resorption and remodeling. It has a triple helical collagen hydrolase activity. Mutations in the gene encoding this protein have been linked to pycnodysostosis.

Physikalische Form

0.5 mg/mL solution in 25 mM Na2HPO4 and 500 mM NaCl (pH 7.0) with 50% glycerol.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable