SML3964

Methylprednisolone acetate

≥98% (HPLC)

• Synonym(e): (6α,11β)-21-(Acetyloxy)-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione acetate, 11β,17α,21-Trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-acetate, 21-Acetoxy-11β,17-dihydroxy-6α-methylpregna-1,4-diene-3,20-dione acetate, 6-Methylprednisolone acetate, Depo-Medro acetatel
• Empirische Formel (Hill-System): C₂₄H₃₂O₆
• CAS-Nummer: 53-36-1
• Molekulargewicht: 416.51
• MDL-Nummer: MFCD00200356
• UNSPSC-Code: 12352200

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Optische Aktivität: [α]/D 85 to 105°, c = 0.5 in chloroform-d
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: -10 to -25°C

Beschreibung

Biochem./physiol. Wirkung

Long-acting anti-inflammatory corticosteroid that suppresses lymphocytes-mediated immunologic responses.



Methylprednisolone acetate (Depo-Medrol) is a long-acting anti-inflammatory corticosteroid that suppresses lymphocytes-mediated immunologic responses. 6-Methylprednisolone acetate binds to intracellular glucocorticoid receptors and inhibits promoter domains of pro-inflammatory genes and hinders secretion of inflammatory cytokines. It effectively treats multiple ailments such as rheumatic and autoimmune diseases, leukemia, multiple myeloma, and Hodgkin’s and non-Hodgkin’s lymphoma symptoms along with other drugs. MPA improves COVID-19 pneumonia prognosis.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Warning
• H-Sätze: H361
• P-Sätze: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Gefahreneinstufungen: Repr. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable