SML3947

PSB12379

≥98% (HPLC)

• Synonym(e): Placeholder name, N-(Phenylmethyl)-adenosine-5′-[hydrogen P-(phosphonomethyl)phosphonate] sodium salt, N6-Benzylpurine riboside-5′-O-[(phosphonomethyl)-phosphonic acid sodium salt
• Empirische Formel (Hill-System): C₁₈H₂₃N₅O₉P₂. xNa
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: white to beige
• Löslichkeit: H₂O: 2 mg/mL, clear
• Lagertemp.: 2-8°C

Beschreibung

Biochem./physiol. Wirkung

Potent and selective ecto-5′-nucleotidase (CD73, eN) Inhibitor.

PSB12379 is a potent and selective ecto-5′-nucleotidase (CD73, eN) Inhibitor (recombinant human/rat eN Ki = 2.21/9.03 nM; human serum eN Ki = 18.8 nM; Ki >>10 μM against NTPDase 1/2/3 & NPP 1/2/3). Umbilical cord mesenchymal stem cell-derived small extracellular vesicles (UCMSC-sEV) is reported to promote the proliferation and migration of pediatric urethral smooth muscle cells (PUSMCs) in cultures by CD73-catalyzed production of adenosine, which can be blocked by PSB12379.

Vorsicht

Hygroscopic

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable