SML2803

Tebanicline hydrochloride

≥98% (HPLC)

• Synonym(e): (R)-5-(2-Azetidinylmethoxy)-2-chloropyridine hydrochloride, (R)-5-(Azetidin-2-ylmethoxy)-2-chloropyridine hydrochloride, 5-((2R)-Azetidin-2-ylmethoxy)-2-chloropyridine hydrochloride, ABT-594 hydrochloride, Ebanicline hydrochloride
• Empirische Formel (Hill-System): C₉H₁₁ClN₂O · xHCl
• CAS-Nummer: 198283-73-7
• Molekulargewicht: 198.65 (free base basis)
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: white to beige
• Löslichkeit: H₂O: 2 mg/mL, clear
• Lagertemp.: −20°C
• InChI: 1S/C9H11ClN2O/c10-9-2-1-8(5-12-9)13-6-7-3-4-11-7/h1-2,5,7,11H,3-4,6H2/t7-/m1/s1
• InChIKey: MKTAGSRKQIGEBH-SSDOTTSWSA-N

Beschreibung

Biochem./physiol. Wirkung

Tebanicline (ABT-594) is a partial agonist at neural nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes. It is a less toxic analog of epibatidine with potent antinociceptive effects.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H336
• P-Sätze: P261 - P271 - P304 + P340 + P312 - P403 + P233 - P405 - P501
• Gefahreneinstufungen: STOT SE 3
• Zielorgane: Central nervous system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable