SML1252

Treosulfan

≥98% (HPLC)

• Synonym(e): (2S,3S)-Butanetetraol 1,4-dimesylate, (2S,3S)-Threitol 1,4-bismethanesulfonate, L-Threitol 1,4-bis(methanesulfonate), NSC 39069, Threosulphan, Treosulphan
• Empirische Formel (Hill-System): C₆H₁₄O₈S₂
• CAS-Nummer: 299-75-2
• Molekulargewicht: 278.30
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Optische Aktivität: [α]/D -4.9 to -5.9°, c = 1 in acetone
• Farbe: white to beige
• Löslichkeit: H₂O: 5 mg/mL, clear
• Lagertemp.: −20°C
• InChI: 1S/C6H14O8S2/c1-15(9,10)13-3-5(7)6(8)4-14-16(2,11)12/h5-8H,3-4H2,1-2H3
• InChIKey: YCPOZVAOBBQLRI-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

Treosulfan is a biofunctional alkylating agent.

Treosulfan is bifunctional alkylating agent.

Treosulfan/l-threitol-1,4-bis-methanesulfonate; dihydroxybusulfan; NSC 39069. It is a prodrug of a bifunctional alkylating cytotoxic agent. Treosulfan can be activated non-enzymatically to two active epoxides. It is used to treat ovarian cancer.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H340,H350,H361f
• P-Sätze: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Gefahreneinstufungen: Carc. 1A - Muta. 1B - Repr. 2
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable