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P3761

Sigma-Aldrich

Pentobarbital Natriumsalz

Synonym(e):

5-Ethyl-5-(1-methylbutyl)-2,4,6-trioxohexahydropyrimidine, Nembutal

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About This Item

Empirische Formel (Hill-System):
C11H17N2NaO3
CAS-Nummer:
57-33-0
Molekulargewicht:
248.25
EG-Nummer:
200-323-9
MDL-Nummer:
MFCD00070198
UNSPSC-Code:
41116107
PubChem Substanz-ID:
24898448

Form

powder

Arzneimittelkontrolle

USDEA Schedule II; Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada

Löslichkeit

H2O: soluble
alcohol: soluble

SMILES String

[Na].CCCC(C)C1(CC)C(=O)NC(=O)NC1=O

InChI

1S/C11H18N2O3.Na.H/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15;;/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16);;

InChIKey

PGOYUXGHADTNIB-UHFFFAOYSA-N

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Anwendung

Pentobarbital sodium salt has been used as an anesthetic in rats and mice prior to various in vitro studies.

Biochem./physiol. Wirkung

Pentobarbital (PB) is a barbiturate and a ligand of the γ-aminobutyric acid subtype A (GABAA) receptor. It is a sedative anesthetic majorly used in rodent euthanasia. Pentobarbital possesses hypnotic functionality and muscle relaxing properties. It enhances GABAergic activity. Intraperitoneal injection of PB may result in loss of righting reflex (LORR) and heartbeat cessation.

Piktogramme

Skull and crossbonesHealth hazard
GHS06,GHS08

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Oral - Repr. 2 - STOT SE 3

Zielorgane

Central nervous system

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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