N0258

N-Nitrosodiethylamin

ISOPAC^®

• Synonym(e): Diethylnitrosamin
• Lineare Formel: (C₂H₅)₂NNO
• CAS-Nummer: 55-18-5
• Molekulargewicht: 102.14
• Beilstein: 1744991
• EG-Nummer: 200-226-1
• MDL-Nummer: MFCD00013890
• UNSPSC-Code: 12352116
• PubChem Substanz-ID: 24897417
• NACRES: NA.25

Eigenschaften

• Form: liquid
• bp: 177 °C (lit.)
• Dichte: 0.95 g/mL (lit.)
• SMILES String: CCN(CC)N=O
• InChI: 1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3
• InChIKey: WBNQDOYYEUMPFS-UHFFFAOYSA-N

Beschreibung

Anwendung

N-Nitrosodiethylamine (NDEA) has been used as a hepatocarcinogen/DNA damaging agent. It has been used as a calibration standard for gas–liquid chromatography.

Biochem./physiol. Wirkung

N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. It is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. NDEA is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. It results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.

Verpackung

Packaged in a 100 mL serum bottle with silicon/PTFE septum and aluminum tear seal.

Vorsicht

Injecting any compatible solvent permits preparation of any desired strength solution without exposure.

Rekonstituierung

Dissolving the contents in 100 mL of solvent yields a 1% solution.

Rechtliche Hinweise

Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H301,H350,H412
• P-Sätze: P202 - P264 - P270 - P273 - P280 - P301 + P310
• Gefahreneinstufungen: Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter