K1750

α-Ketoglutarsäure

≥98.5% (NaOH, titration)

• Synonym(e): 2-Oxo-glutarsäure, 2-Oxopentandisäure
• Lineare Formel: HOOCCH₂CH₂COCOOH
• CAS-Nummer: 328-50-7
• Molekulargewicht: 146.10
• Beilstein: 1705689
• EG-Nummer: 206-330-3
• MDL-Nummer: MFCD00004165
• UNSPSC-Code: 12352204
• PubChem Substanz-ID: 57654314
• NACRES: NA.32

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥98.5% (NaOH, titration)
• Form: powder
• Löslichkeit: water: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
• Lagertemp.: 2-8°C
• SMILES String: OC(=O)CCC(=O)C(O)=O
• InChI: 1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
• InChIKey: KPGXRSRHYNQIFN-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

α-Ketoglutaric acid (α-KG) is produced in the tricarboxylic acid cycle.[1]

Anwendung

α-Ketoglutaric acid (α-KG) has been used:

• to study its effects on swine fecal microflora in an in vitro fermentation system[2]
• to study its effects on the activation of CD8⁺ T-cells[3]
• as a substrate in glutamate oxaloacetate transaminase (GOT2) mitochondrial lysate assay[4]

Biochem./physiol. Wirkung

α-Ketoglutaric acid (α-KG) has a wide range of applications in the animal feed, food, pharmaceutical and fine chemistry industries.[1]

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H318
• P-Sätze: P280 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Dam. 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves