Y0000155

Tramadolhydrochlorid -hydrochlorid

European Pharmacopoeia (EP) Reference Standard

• Synonym(e): (±)-cis-2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)-cyclohexanol -hydrochlorid -hydrochlorid
• Empirische Formel (Hill-System): C₁₆H₂₅NO₂ · HCl
• CAS-Nummer: 36282-47-0
• Molekulargewicht: 299.84
• MDL-Nummer: MFCD00798507
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329830868
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: tramadol
• Hersteller/Markenname: EDQM
• Arzneimittelkontrolle: USDEA Schedule IV
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: Cl.COc1cccc(c1)[C@@]2(O)CCCC[C@@H]2CN(C)C
• InChI: 1S/C16H25NO2.ClH/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3;/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3;1H/t14-,16+;/m1./s1
• InChIKey: PPKXEPBICJTCRU-XMZRARIVSA-N

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Tramadol is a synthetic opiate agonist analgesic, widely used in patients suffering from moderate to severe chronic pain.[1][2] It is considered safe when compared to other opioids. It contributes to the analgesic activity by blocking the nociceptive impulses at the spinal level, inhibiting the norepinephrine and serotonin reuptake.[2]

Anwendung

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

Biochem./physiol. Wirkung

Opioidanalgetikum; P450-Substrat.

Verpackung

Dieses Produkt wird, wie von der entsprechenden Pharmakopöe geliefert, angeboten. Die aktuellen Mengeneinheiten finden Sie im Referenzsubstanzen-Katalog der EDQM.

Sonstige Hinweise

Kann Verkaufsbeschränkungen unterliegen.

Sicherheitshinweise

• Piktogramme: GHS06,GHS09
• Signalwort: Danger
• H-Sätze: H301,H336,H411
• P-Sätze: P261 - P264 - P271 - P273 - P301 + P310 - P304 + P340 + P312
• Gefahreneinstufungen: Acute Tox. 3 Oral - Aquatic Chronic 2 - STOT SE 3
• Zielorgane: Central nervous system
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable